HORMONAL TREATMENT OF ENDOMETRIOSIS: PRIMOLUT N
Primolut N is a hormonal drug occasionally used to treat endometriosis. It is also sometimes used to treat a variety of other conditions including abnormal uterine bleeding, amenorrhoea (absence of periods) and PMS (premenstrual syndrome).
Primolut N is a progestogen (a synthetic progesterone) derived from the male hormone testosterone. Its chemical name is norethisterone. It is manufactured by Schering and sold in the form of white 5 milligram tablets.
How Primolut N works
It is thought that Primolut N eradicates endometrial implants by suppressing ovulation and interfering with the growth of the misplaced endometrial cells, causing them to slowly waste away Most women will stop ovulating and menstruating during their course of Primolut N.
Dosages of Primolut N generally used
Gynaecologists usually recommend 5 to 20 milligrams of Primolut N per day (one to four tablets per day) for four to nine months.
The more common side effects are depression, weight gain, malaise, lethargy and tiredness, acne, vaginal bleeding, decreased libido and nausea.
How effective is Primolut N
There are no reliable figures on the effectiveness of Primolut N for the treatment of endometriosis.
Primolut N, pregnancy and breastfeeding
Primolut N should not be used during pregnancy as progestogens derived from testosterone can cause abnormalities in the developing foetus.
The use of Primolut N while breastfeeding is not recommended, as small amounts of progestogens have been found in the milk of mothers taking them and the effect on the child is not known.
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Tags: Women’s Health